HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.
Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Irina Stoyanova
Keynote Presentation
Irina Stoyanova, Medical University of Varna, Bulgaria

The increase in human lifespan during the last century is accompanied by an increased risk for development of age-related disorders including neurodegenerative diseases (NDD) such as Alzheimer’s and Parkinson’s disease. These pathologies are characterised by impairmen [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Benyi Li
Keynote Presentation
Benyi Li, University of Kansas, United States

Abstract: Alzheimer’s disease (AD) is a progressive neuronal degenerative disorder and sleep disorders have been linked to Alzheimer’s disease progression in addition to the typical symptoms of progressive loss of memory, speech, and cognition. Sleep behaviour changes [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Mark S Kindy
Keynote Presentation
Mark S Kindy, University of South Florida and the James A. Haley VA Hospital, United States

Serum amyloid P component (SAP) is found in all amyloids and studies have suggested that it plays an integral role in the formation, progression, and maintenance of the disease processes. The mouse SAP (mSAP) does not interact with human proteins and since most of the models for [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Don Kulasiri
Oral Presentation
Don Kulasiri, Lincoln University, New Zealand

Alzheimer’s disease (AD) as the leading cause of dementia affects millions of families across the world. AD causes huge physical social, psychological and financial impacts not only on the patients but also on their families and the whole society. Numerous research has been [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Yung-Feng Liao
Oral Presentation
Yung-Feng Liao, Academia Sinica, Taiwan

Alzheimer's disease (AD) is characterized by a chronic decline in cognitive function and is pathologically typified by cerebral deposition of amyloid-β peptide (Aβ). The production of Aβ is mediated by sequential proteolysis of amyloid precursor protein (APP) b [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Ravi Samuel
Oral Presentation
Ravi Samuel, The Psychotherapy Clinic, India

The prevalence of Dementia is on the rise due to increasing longevity. In addition, co-morbid medical conditions and depression lead to the onset of cognitive impairment - the prevalence of medical ailments like diabetes mellitus, hypertension, and depression are high among the e [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Jingyi Liang
Oral Presentation
Jingyi Liang, UiT The Arctic University of Norway, Norway

Alzheimer’s disease (AD) as the leading cause of dementia affects millions of families across the world. AD causes huge physical social, psychological and financial impacts not only on the patients but also on their families and the whole society. Numerous research has been [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Shubhangi Pingle
Oral Presentation
Shubhangi Pingle, Regional Occupational Health Centre (Southern), NIOH, India

The interaction between proteomic profiling and Alzheimer's disease, Dementia in industrial workers was not explored in occupational settings. Therefore, the present study, aimed to assess the proteomic profiling with among workers exposed to Pb with contemplation of varied b [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Anand Krishna Tiwari
Oral Presentation
Anand Krishna Tiwari, Institute of Advanced Research, India

Alzheimer’s disease (AD) is a neurodegenerative disease, characterized by loss of memory and cognitive impairment due to the accumulation amyloid beta 42 (Aβ42) plaque and neurofibrillary tangles (NFT) due the hyperphosphorylated Tau protein in the parts of brain. Due [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Stefan Milanov Ivanov
Oral Presentation
Stefan Milanov Ivanov, Redesign Science, United States

Many gaps in our understanding of Alzheimer’s disease (AD) remain despite intense research efforts. Perhaps the most prominent gap is the mechanism of tau condensation and fibrillization. One viewpoint is that positively charged tau is condensed by cytosolic polyanions. How [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Amir Khcharem
Oral Presentation
Amir Khcharem, University of Sfax, Tunisia

Background: Various pharmacological aids are used to counteract the detrimental effects of sleep loss on exercise, such as caffeine. However, studies examining the possible protective impact of caffeine against reactive oxygen species (ROS) at the level of cell and tissue culture [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Leila Hosseini
Oral Presentation
Leila Hosseini, Tabriz University of Medical Sciences, Iran (Islamic Republic of)

Abstract: In the current aging society, the number of patients suffering from Alzheimer’s disease (AD) is rapidly increasing, and without therapeutic breakthroughs is estimated to reach 80 million by 2040. As an irreversible chronic neurodegenerative disease, AD is chara [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Manuel Narváez Peláez
Oral Presentation
Manuel Narváez Peláez, Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Spain

Dysregulation of hippocampal neurogenesis is linked to several neurodegenereative diseases, where boosting hippocampal neurogenesis in these patients emerges as a potential therapeutic approach. Accumulating evidence for Neuropeptide Y (NPY) and galanin (GAL) interaction was show [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Cristina Pacheco Soares
Oral Presentation
Cristina Pacheco Soares, Universidade do Vale do Paraiba, Brazil

The limited repair capacity of the central nervous system (CNS) is a viable challenge. Alzheimer's disease (AD) is a progressive and highly prevalent neurodegenerative disease that affects people worldwide. The complete  inclusion of the CNS is not yet possible by m [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Claudia Colussi
Oral Presentation
Claudia Colussi, Istituto di Analisi dei Sistemi ed Informatica "Antonio Ruberti" (IASI) , Italy

Reduction of adult hippocampal neurogenesis is an early critical event in Alzheimer’s disease (AD), leading to progressive memory loss and cognitive decline. The nucleoporin Nup153, besides its role in nuclear transport, has been described as a key regulator of NSC plastici [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Kesheng Wang
Oral Presentation
Kesheng Wang, West Virginia University, United States

Background: Proteins play an important role in disease pathways and drug-target discovery. The most widely used biomarkers for Alzheimer’s disease (AD) include the apolipoprotein E (APOE) protein, the clinical cerebrospinal fluid (CSF) protein biomarkers of Aβ plaques [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Danqing Xiao
Oral Presentation
Danqing Xiao, Regis College, United States

White matter (WM) degeneration is suggested to predict the early signs of Alzheimer disease (AD). The exact structure regions of brain circuitry involved is not clear. This study aims to examine the associations between WM tract integrity, specifically the specific diffusion tens [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Xiaobo Mao
Oral Presentation
Xiaobo Mao, Johns Hopkins School of Medicine, United States

α-Synucleinopathies is characterized with accumulation of misfolded α-synuclein (α-syn), including Parkinson’s disease (PD), Dementia with Lewy Bodies (DLB), and Multiple System Atrophy (MSA). Emerging evidence indicates that pathogenesis of α-synucl [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Subramanian Boopathi
Oral Presentation
Subramanian Boopathi, Universidad Nacional Autónoma de México, Mexico

Over 50 million people succumbed to Alzheimer’s disease (AD) worldwide. Unless scientists predict effective therapeutic strategies, this number will reach 150 million by 2050. AD is characterized by progressive neurodegeneration associated with Amyloid β (Aβ) [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Mario Allegra
Keynote Presentation
Mario Allegra, University of Palermo, Italy

Abstract:Overnutrition and modern diets containing high proportions of saturated fat are amongst the major factors responsible for the development of low-grade, systemic, chronic inflammation, hyperglycaemia and dyslipidaemia. These conditions may eventually lead to insulin resis [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Jun Hua
Keynote Presentation
Jun Hua, Johns Hopkins University School of Medicine, United States

Abstract:  In the brain, small pial arteries and arterioles with diameters up to 100-150 microns is the primary regulator of local tissue perfusion for the delivery of oxygen and nutrients to meet the metabolic demands from neurons and other cells. Recently, cerebral lympha [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Yong Xiao Wang
Keynote Presentation
Yong Xiao Wang, Albany Medical College, United States

Alzheimer’s disease (AD) and AD-related dementias (ADRD) are the common incurable neurodegenerative conditions characterized by progressive cognitive deterioration, memory decline and even death. The major forms of ADRD include vascular contributions to cognitive impai [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Esther Ebenezer
Oral Presentation
Esther Ebenezer, UniKL Royal College of Medicine Perak, Malaysia

Alzheimer’s dementia is a neurodegenerative disorder that commonly affects the elderly was first described in 1906. Since then over a century researchers and medical professionals have made remarkable advances together with various organisations and fund providers in develo [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Anthony Pak-Hin Kong
Oral Presentation
Anthony Pak-Hin Kong, The University of Hong Kong, Hong Kong

Memory decline and impairments occur predominantly in people with dementia (PWD). Deficits in episodic and verbal short-term memory (vSTM) have been widely reported in PWD. Analysis of spoken spontaneous discourse is becoming more popular in dementia research as well as clinical [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Esther Ebenezer
Oral Presentation
Esther Ebenezer, UniKL Royal College of Medicine Perak, Malaysia

Malaysia is rapidly ageing with declining number of younger age groups and the young old surpassing the other older groups. As dementia is a age related neuro-degenerative disease of the brain, more and more older people will be inflicted with dementia and this silent epidemic wi [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Rui Yuan Pan
Oral Presentation
Rui Yuan Pan, Beijing Institute of Basic Medical Sciences, China

Neuroinflammation is a hallmark of Alzheimer’s disease (AD). Microglia are the resident immune cells in the central nerves system (CNS) and function in many aspects of neuroinflammation. The immune functions of microglia such as surveillance and clearance are gradually lost [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Jianshe Yang
Oral Presentation
Jianshe Yang, Gansu Medical College, China

Coronavirus disease 2019 (COVID-19) is a multi-organ and multi-system disease, associated with high morbidity and mortality due to pulmonary and cardiovascular involvement, and attended by various neurological and psychiatric (N and P) manifestations during its acute and subseque [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Juliet Stromin
Oral Presentation
Juliet Stromin, University of Cape Town, South Africa

In late 2019, the world was introduced to the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pathogen, a strain of the coronavirus which has caused the respiratory illness termed Covid-19 (coronavirus 2019; Wong, 2021). At the time of writing, there has been a repor [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Alves Da Costa
Oral Presentation
Alves Da Costa, University of the Côte d'Azur, France

Mitophagy and mitochondrial dynamics alterations are two major hallmarks of neurodegenerative diseases. Dysfunctional mitochondria accumulate in Alzheimer’s diseaseaffected brains by yet unexplained mechanisms We show that presenilins 1 and 2 trigger opposite e [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Jose-Luis Gomez-Ariza
Oral Presentation
Jose-Luis Gomez-Ariza, University of Huelva, Spain

Neurodegenerative diseases associated to aging are one of the most important social, human, family and economic problems of this century, whose etiology, pathology, early symptoms and evolution are not well known. Therefore, the development and application of new methodologies ar [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Izaskun Buendia
Oral Presentation
Izaskun Buendia, University of Santiago de Compostela, Spain

The myelin sheaths that cover the axons are essential for the conduction of nerve impulses in the nervous system. In this regard, mature oligodendrocytes are the myelinating cells of the central nervous system (CNS). In recent decades, research on the mechanisms involved in myeli [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Liuhua Shi
Oral Presentation
Liuhua Shi, Emory University, United States

Epidemiological evidence suggests air pollution exposure may increase risk of Alzheimer’s disease and related dementias (ADRD). However, previous U.S. studies have predominantly focused on hospitalizations, which fails to fully capture ADRD. Here we constructed two national [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Maria Eugenia Ariza
Oral Presentation
Maria Eugenia Ariza, The Ohio State University Wexner Medical Center, United States

Abstract: We have previously reported that the dUTPase protein from human herpesvirus 6A (HHV-6A) and Epstein-Barr virus (EBV) increased the expression and secretion of pro-inflammatory cytokines from hDCs in a TLR2-dependent manner. Because IL-1β and IL-6 can disrupt the [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Jianrong Tang
Oral Presentation
Jianrong Tang, Baylor College of Medicine, United States

Cognitive impairment is a core feature of cyclin-dependent kinase-like 5 (CDKL5) deficiency, a neurodevelopmental disorder characterized by early epileptic seizures, intellectual disability, and autistic behaviors. Although loss of CDKL5 affects a number of molecular pathways, ve [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Chun Xu
Oral Presentation
Chun Xu, University of Texas Rio Grande Valley, United States

Alzheimer's disease (AD), a main cause of dementia is known to have a strong genetic component to its development and is often comorbid with neuropsychiatric conditions. In addition, certain neuropsychiatric disorders are considered as early indicators of AD and present when [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Elias Mazrooei Rad
Poster Presentation
Elias Mazrooei Rad, Khavaran Higher Education Institute, Iran (Islamic Republic of)

Alzheimer's disease is a progressive degenerative disease commonly seen in the elderly. Symptoms of this disease include memory loss, judgment and important behavioral changes in the person. The main purpose and motivation of this study was to design and present a model for t [....] » Read More

Speaker at International Alzheimer’s Disease & Dementia Conference 2022 - Maria Tsamou
Poster Presentation
Maria Tsamou, ToxGenSolutions BV, Netherlands

Abstract: Sporadic (late-onset) Alzheimer’s disease (sAD) is a progressive neurodegenerative age-related disease, caused by interaction of genetic and environmental factors, leading to brain damage accompanied by memory loss and cognitive impairment. Up till now, animal- [....] » Read More

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