Abnormal brain alterations in Alzheimer's disease and dementia involve progressive changes that disrupt normal brain function. In Alzheimer's, these alterations include the accumulation of beta-amyloid plaques outside neurons and tau protein tangles within neurons, leading to neuronal death and brain tissue loss. These changes primarily affect memory, cognition, and behavior. In dementia, which can have various causes including Alzheimer's, vascular issues, or Lewy body disease, abnormal alterations may differ but generally involve similar consequences for brain function. Understanding these alterations is crucial for developing effective treatments and interventions aimed at slowing progression or alleviating symptoms. Research continues to explore the complex mechanisms behind these brain alterations to improve diagnostic methods and therapeutic strategies for individuals affected by these debilitating conditions
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States