Apathy is a common and challenging symptom in Alzheimer’s Disease and Dementia, characterized by a lack of motivation, interest, and emotional response. It affects up to 70% of individuals with these conditions and significantly impacts their quality of life and caregiver burden. Unlike depression, apathy in dementia is not necessarily accompanied by sadness or hopelessness but manifests as a withdrawal from activities and social interactions. This symptom can stem from neurodegenerative changes in the brain, particularly in areas responsible for motivation and emotion regulation, such as the frontal lobes. Addressing apathy requires a multifaceted approach, including personalized activities, social engagement, and sometimes pharmacological interventions, to enhance the individual's involvement and overall well-being.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States