Apoptosis, or programmed cell death, plays a critical role in Alzheimer's disease (AD) pathogenesis. In AD, neurons undergo apoptosis due to various factors, including accumulation of beta-amyloid plaques and neurofibrillary tangles composed of hyperphosphorylated tau protein. These abnormalities disrupt cellular function and lead to neuronal death, contributing to the progressive cognitive decline observed in AD patients. Understanding the mechanisms of apoptosis in AD is crucial for developing therapeutic strategies aimed at preserving neuronal integrity and slowing disease progression. Research focuses on interventions that can modulate apoptotic pathways to protect neurons from degeneration, offering hope for future treatments that may alleviate symptoms and improve quality of life for those affected by this devastating neurodegenerative disorder.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States