Cerebrospinal fluid (CSF) plays a crucial role in Alzheimer's Disease (AD) and dementia research. In AD, abnormal accumulation of proteins like amyloid-beta and tau in the brain leads to cognitive decline. CSF acts as a conduit for these biomarkers, reflecting changes in their levels. Researchers use CSF analysis to detect early signs of AD by measuring amyloid-beta and tau proteins. Elevated levels of tau and decreased amyloid-beta in CSF are indicative of neurodegeneration and correlate with cognitive impairment. This fluid also helps in drug development, as changes in biomarkers can indicate treatment effectiveness. Understanding CSF dynamics enhances diagnostic accuracy and provides insights into disease progression, offering hope for earlier interventions and improved management strategies for AD and related dementias.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States