Central nervous system (CNS) neurodegenerative disorders like Alzheimer's disease and dementia are characterized by progressive deterioration of cognitive function and memory. Alzheimer's disease, the most common form of dementia, involves the accumulation of beta-amyloid plaques and tau protein tangles in the brain, leading to neuronal death and synaptic dysfunction. Symptoms typically include memory loss, confusion, and impaired judgment, ultimately affecting daily functioning.
Dementia, a broader category, encompasses various conditions marked by cognitive decline affecting language, reasoning, and behavior. Both disorders pose significant challenges to patients, caregivers, and healthcare systems due to their chronic and debilitating nature. Current research focuses on understanding the underlying mechanisms, developing biomarkers for early diagnosis, and exploring potential therapies to slow disease progression. Effective management involves multidisciplinary approaches tailored to individual needs, aiming to improve quality of life and provide support for patients and their families.
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States