"Estrogen-related dementia" refers to cognitive decline linked to reduced estrogen levels, primarily in postmenopausal women. Estrogen plays a critical role in brain functions like memory and cognition, potentially safeguarding against Alzheimer's disease and other forms of dementia by supporting synaptic activity, reducing beta-amyloid plaques, and promoting neuronal survival.
Following menopause, declining estrogen levels may heighten the risk of cognitive impairment. Hormone replacement therapy (HRT) has been explored as a potential strategy to counteract this decline, though its benefits and risks remain under scrutiny. A deeper understanding of how estrogen influences dementia can guide the development of targeted therapies aimed at preserving cognitive health, particularly in aging women.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States