Dementia, including Alzheimer’s Disease, often presents with distinct motor features that progressively impair physical function. Early in the disease, subtle changes such as slowed movements and difficulty with coordination may be observed. As dementia progresses, more pronounced motor symptoms can develop, including bradykinesia (slowness of movement), rigidity, and tremors similar to those seen in Parkinson's disease. Gait disturbances are common, leading to shuffling steps, instability, and an increased risk of falls. In advanced stages, muscle weakness and loss of fine motor skills can make everyday activities like dressing and eating challenging. These motor impairments, coupled with cognitive decline, significantly impact the quality of life and independence of individuals with dementia.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States