The subgenual anterior cingulate cortex (sgACC) plays a crucial role in Alzheimer's Disease (AD) and dementia. Research indicates that alterations in this region are associated with cognitive decline and emotional dysregulation, both common symptoms in these conditions. In AD, the sgACC shows structural changes such as reduced volume and altered connectivity, impacting mood regulation and memory consolidation. Functionally, it's involved in processing emotional responses and integrating them with cognitive functions, suggesting its role in behavioral changes seen in dementia patients. Understanding sgACC dysfunction could lead to targeted therapies aiming to preserve cognitive function and emotional well-being in individuals with AD and other forms of dementia, potentially improving their quality of life.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States