Tauopathies are a class of neurodegenerative diseases characterized by the abnormal aggregation of tau protein in the brain. In Alzheimer's disease, tau proteins become hyperphosphorylated and form neurofibrillary tangles, disrupting neuronal function. This accumulation leads to cell death and is a hallmark of dementia. Unlike other dementias that might involve amyloid plaques, tauopathies primarily focus on the tau protein abnormalities. Understanding tau pathology is crucial for developing targeted therapies aimed at stabilizing tau or preventing its aggregation. Research into tauopathies not only aids in comprehending Alzheimer’s disease but also provides insights into other tau-related disorders, offering broader implications for neurodegenerative disease treatment.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States