Genetics play a significant role in Alzheimer's disease and dementia. Research indicates that certain genes, such as the APOE gene, increase susceptibility to Alzheimer's. APOE variants like APOE ε4 are associated with higher risk, while APOE ε2 may have a protective effect. Beyond APOE, other genes related to inflammation, cholesterol metabolism, and neuronal function also influence dementia risk. However, genetics alone do not determine the onset of these conditions; environmental factors and lifestyle choices also play crucial roles. Understanding genetic predispositions helps in early detection and personalized treatment strategies. Ongoing research aims to unravel complex genetic interactions that could lead to better prevention and management of Alzheimer's disease and dementia.
Jacqueline Tuppen
Cogs Club, United Kingdom
Yong Xiao Wang
Albany Medical College, United States
Kaoru Sakatani
The University of Tokyo, Japan
Suren A Tatulian
University of Central Florida, United States
Constantina Mizis
The Latino Alzheimer’s and Memory Disorders Alliance, United States
Paul Y Song
NKGen Biotech, United States
Marco Ruggiero
Silver Spring Sagl, Switzerland
Title : Cerebral vascular calcium signaling in diabetic alzheimer's disease-related dementias
Yong Xiao Wang, Albany Medical College, United States
Title : Deep learning-based risk assessment of cognitive impairment using health examination data
Kaoru Sakatani, The University of Tokyo, Japan
Title : Evaluation of the neuroprotective potential of indicaxanthin from opuntia ficus indica fruit against dysmetabolism-related neurodegeneration both in vivo and in vitro
Mario Allegra, University of Palermo, Italy
Title : Cogs Club: Making a difference
Jacqueline Tuppen, Cogs Club, United Kingdom
Title : Development of imaging based biomarkers for neurovascular abnormalities in neurodegenerative diseases
Jun Hua, Johns Hopkins University School of Medicine, United States
Title : Psychosocial considerations in management of corticobasal degeneration
Esraa Askar, Forest Hills Hospital, United States